Anti-microbial hand towel with time-delay chromatic transfer indicator and absorbency rate delay

ABSTRACT

A disposable paper towel with an anti-microbial lotion and is provided with a chromatic transfer indicator which undergoes a delayed, visually perceptible color change at a predetermined time after the towel is wetted. An anti-microbial lotion on the towel increases water absorbency times (WAR) to further promote lotion transfer to the skin and increase lotion transfer effectiveness.

CLAIM FOR PRIORITY

This application is based upon U.S. Provisional Patent Application Ser.No. 60/786,819, filed Mar. 28, 2006, of the same title. The priority ofU.S. Patent Application Ser. No. 60/786,819 is hereby claimed and thedisclosure thereof incorporated into this application by reference.

TECHNICAL FIELD

The present invention relates to paper towels used as hand towels. In apreferred embodiment the present invention is directed to ananti-microbial hand towel with a time-delay chromatic transfer indicatorwhich undergoes a visually perceptible color change at a predeterminedtime after the towel is wetted with, wet hands, for example. Ananti-microbial lotion on the towel increases water absorbency times(WAR) to further promote lotion transfer to the skin and increasetransfer effectiveness.

BACKGROUND

Frequent hand washing is a simple and effective means to ensure properhygiene and prevent contamination of food and the spread of disease.Complex systems have been proposed to encourage food service and healthcare workers to adequately cleanse their hands frequently, in view ofthe relatively high potential for undesirable contamination associatedwith their activities.

Washing of the skin, especially the hands, with anti-microbial soapformulations can remove many viruses and bacteria from the washedsurfaces. Removal of the viruses and bacteria is due to the surfactancyof the soap and the mechanical action of the wash procedure. Therefore,it is known and recommended that the people wash frequently to reducethe spread of viruses and bacteria. Recent surveys, however, haverevealed that while nearly 95% of people claim to have washed theirhands after use of public restrooms, actual observations reveal thatthis figure does not exceed about 66%. Notwithstanding increasedawareness, there is a tendency to rush the hand washing process whichleads to inadequate hygiene. A number systems and devices to encouragelonger and more thorough hand washing have accordingly been developed.

Collopy in U.S. Pat. No. 6,832,916 discloses a hand-washing devicecontaining a display panel that encourages the user to wash their handsfor about 15 seconds to remove germs. Gorra, U.S. Pat. No. 5,945,910discloses method and apparatus for monitoring and reporting handwashing, which includes a sensor for signaling the dispensation of acleaning agent from a dispenser, and a reporting and monitoring module.Allen et al., U.S. Pat. No. 5,781,942 discloses wash stations and methodof operation, which monitors hand washing and assists in hand washing.These systems are relatively expensive and difficult to implement;oftentimes involving training and monitoring personnel. Even when suchsteps have been taken, there is little certainty that all personnel havefollowed proper washing procedures.

Frequent hand washing has the drawback that harsh soaps and cleansingagents can irritate the skin and damage the acid mantle of the skin.

Cellulosic substrates coated with lotions are well known in the art. Forexample, U.S. Pat. No. 5,665,426 to Krzysik et al., is directed towardsa lotion formula that can be applied to a tissue, which transfers thelotion to the user's skin in order to reduce irritation and redness.U.S. Pat. No. 5,871,763 to Luu et al., as well is directed towards alotion formula that is applied to a substrate for skin care treatment.The lotion composition of '763 is melted by the heat produced by thehands of a user of the cellulosic substrate to enable the lotion'stransfer to the user's skin. Another lotion-treated substrate isdescribed in U.S. Pat. No. 5,525,345 to Warner et al. The lotioncomposition of '345 comprises a plastic or fluid emollient that is solidor semi solid at room temperature and an immobilizing agent with amelting point above room temperature, which stabilizes the lotioncomposition on the surface of the substrate. See also U.S. applicationSer. No. 10/483,633 (Publication No. US 2005/0031847), where twoseparate and distinct phases, lipid and aqueous, are applied to asubstrate to facilitate cleansing of skin. Further, there is describedin U.S. Pat. No. 4,987,632 to Rowe et al., a cleaning wipe treated witha composition containing detergent, which is leached out upon contactwith water.

There are also known lotions containing anti-microbial and pH balancingagents to protect the skin. For example, U.S. Pat. No. 6,238,682 toKlofta et al. is directed towards a tissue treated with anhydrous skinlotion containing anti-microbial components in addition to hydrophilicsolvents and surfactants. See also U.S. Pat. No. 6,352,700 to Luu etal., which is directed towards a substrate treated with a lotion thatcontains a skin pH balancing compound for maintaining a proper skin acidmantle. Other lotions containing anti-microbial agents include U.S.patent application Ser. No. 10/608,661 (Publication No. US2004/0039353), which is directed towards wet wipes containing a Yuccaspecies extract as an anti-microbial agent; U.S. patent application Ser.No. 09/851,273 (Publication No. US 2002/0031486), which is directedtowards an anti-microbial cleansing composition, containing little or novolatile alcohol, that may be used alone or in combination with lotionsand the like; U.S. Pat. No. 6,436,885 to Biedermann et al., which isdirected towards an anti-microbial cleansing compositions that has a pHof from about 2 to about 5.5; U.S. Pat. No. 6,383,505 to Kaiser et al.which is directed towards an anti-microbial lotion for topical use in aform of oil-in-water emulsion; additionally, similar subject matter isdisclosed in U.S. Pat. No. 6,482,423 to Beerse et al.; U.S. Pat. No.6,488,943 to Beerse et al.; U.S. Pat. No. 6,284,259 to Beerse et al.;U.S. Pat. No. 6,258,368 to Beerse et al.; U.S. Pat. No. 6,183,763 toBeerse et al.; and U.S. Pat. No. 6,210,695 to Beerse et al., as well.

Color indicators are known, for example, to indicate degree of wetness.For example, U.S. patent application Ser. No. 10/806,711 (PublicationNo. US 2004/0191118) is directed towards a single/multi-layermicroporous composite material, containing dispersed pH-sensitivecomponent, which can be embedded in food packaging or diapers toindicate high moisture concentration. The components of the compositematerial are selected to target specific fluids and regulate theirdiffusion rate. A single layer composite containing 4% pH indicatingagent and 25% fluid regulating additive (to increase diffusion rate) maychange its color in less than 30 seconds. Some other wetness indicatorsspecifically address wearable articles such as diapers. Note, forexample U.S. Pat. No. 6,904,865 to Klofta et al.; U.S. Pat. No.6,949,089 to Olson et al.; U.S. Pat. No. 5,690,624 to Sasaki et al.;U.S. Pat. No. 4,705,513 to Sheldon et al.; as well as U.S. Pat. No.4,231,370 to Mroz et al. U.S. patent application Ser. No. 10/134,207(Publication No. US 2003/0206940) is directed towards a cosmetic mixturecontaining a benefit agent and a color dye that are applied to adisposable personal care item. Saturation of the personal care item withwater foams the cosmetic mixture and enables its application to skin orhair. Fading of the color dye from the personal care item indicatesreduced concentration of the cosmetic mixture in the personal care itemand its transfer into the skin or hair of the user. Another example isU.S. Pat. No. 6,733,766 to Gott et al., which is directed towards apersonal care composition containing a hydrophobic carrier andhydrophilic colorant, which becomes visually perceivable upon contactwith water. U.S. Pat. No. 6,309,655 to Minnix is directed towards acosmetic anhydrous composition that upon contact with wet skin generatesheat, which disintegrates or dissolves granules, embedded within thecomposition; the granules release a color dye to indicate to the useroptimal degree of mixing between the water and the composition. U.S.Pat. No. 6,270,783 to Slavtcheff et al. is directed towards a cosmeticcomposition, containing a thermochromic substance and exothermic orendothermic agent, which reacts with moisture within the skin togenerate heat, and subsequently, change the color of the composition.U.S. Pat. No. 6,007,797 to Bell et al. is directed towards a colorsunscreen composition that includes at least one oil soluble dye, whichis dissipated as the sunscreen is rubbed into the skin. U.S. Pat. No.4,029,598 to Neisius et al. is directed towards a pH sensitive indicatorazo-dyes used in connection with cellulose or other carriers.

The following are also of interest with respect to active graphics ondisposable products: U.S. Pat. No. 6,307,119 to Cammata et al.; U.S.Pat. No. 6,297,424 to Olsen et al. and U.S. patent application Ser. No.11/043,571 (Publication No. US 2005/0160543).

Despite plentiful art, there exists a need for simple and effectivemeans for promoting hygiene and skin care concurrently in connectionwith hand washing. The present invention provides a disposable papertowel with an anti-microbial skin care lotion and transfer indicatorresponsive to a pH balancing agent to promote effective transfer of thelotion to the skin.

SUMMARY OF THE INVENTION

Generally speaking, the present invention provides lotioned towel whichprovides skin care and anti-microbial activity. Numerous attributes makethe lotioned towels of the invention especially suitable for towels usedby healthcare and food service workers. In one preferred embodiment, apH balancing agent and pH sensitive transfer indicator are selected andapplied to the web such that a pH sensitive transfer indicator undergoesa gradual color change as the towel is used.

Another aspect of the invention involves increased WAR times. Thislatter feature, while usually undesirable in a towel product, promotesanti-microbial lotion transfer to the skin as well, since a user willrub the towel longer when drying his or her hands. Accordingly, morerecycle fiber in the product can actually be beneficial to the product'sperformance due to the associated increase in absorption time commonlyseen with increased levels of recycle fiber. Lotion transfer isextremely important for both skin care and anti-microbial effectivenessas will be appreciated by one of skill in the art.

Further aspects of the invention are enumerated below and discussed indetail in connection with the various Figures and examples hereinafterprovided.

There is provided in a first aspect of the invention an anti-microbialpaper towel with a chromatic transfer indicator including a cellulosicweb; a transferable lotion composition comprising an emollient andanti-microbial agent, the lotion composition being immobilized on thecellulosic web in a semi-solid or solid form. The transferable lotioncomposition is selected from lotion compositions which are transferableupon contact with water or lotion compositions which are transferableupon application of heat. There is further provided a water soluble pHbalancing agent disposed on the web and a pH-sensitive transferindicator disposed on the web. The pH-sensitive transfer indicator ischromatically responsive to the pH balancing agent in aqueous form. ThepH balancing agent and pH-sensitive transfer indicator are selected andapplied to the web such that the pH-sensitive transfer indicatorundergoes a gradual color change upon contact with water. Generally, thelotion composition includes from about 0.01 percent by weight to about10 percent by weight of an anti-microbial agent; more typically thelotion composition comprises from about 0.05 percent by weight to about5 percent by weight anti-microbial agent. Suitable anti-microbial agentsare selected from: 2,4,4′-trichloro-2′-hydroxydiphenyl ether(triclosan); 3,4,4′-trichlorocarbanilide (triclocarban);3,4,4′-trifluoromethyl-4,4′-d-ichlorocarbanilide (cloflucarban);5-chloro-2-methyl-4-isothiazolin-3-one; iodopropynlbutylcarbamate;8-hydroxyquinoline; 8-hydroxyquinoline citrate; 8-hydroxyquinolinesulfate; 4-chloro-3,5-xylenol(chloroxylenol);2-bromo-2-nitropropane-1,3-diol; diazolidinyl urea; butoconazole;nystatin; terconazole; nitrofurantoin; phenazopyridine; acyclovir;clortrimazole; chloroxylenol; chlorhexidine; chlorhexidine gluconate;miconazole; terconazole; butylparaben; ethylparaben; methylparaben;methylchloroisothiazoline; methylisothiazoline; a mixture of1,3-bis(hydroxymethyl)-5,5-dimethylhydantoin and 3-iodo-2-propynyl butylcarbamate; oxyquinoline; EDTA; tetrasodium EDTA; p-hydroxyl benzoic acidester; alkyl pyridinum compounds; coco phosphatidyl PG-dimoniumchloride; chlorhexidene digluconate; chlorhexidene acetate;chlorhexidene isethionate; chlorhexidene hydrochloride; benzalkoniumchloride; benzethonium chloride; polyhexamethylene biguanide; andmixtures thereof. So also, the anti-microbial agent may include a zincsalt.

The pH balancing agent typically includes an organic acid and optionallyincludes an organic acid/buffer combination such as citric acid anddisodium phosphate. Another suitable buffer combination may includedisodium citrate and sodium hydroxide. The pH balancing agent isgenerally applied to the web in an amount of from about 0.5 percent byweight to about 3 percent by weight of the lotion composition. Moretypically the pH balancing agent is applied to the web in an amount offrom about 1 percent by weight to about 2 percent by weight of thelotion composition. The pH balancing agent may include an alpha hydroxyacid, an alpha di-hydroxy acid, a beta hydroxy acid or combinationsthereof.

Suitable pH balancing agents are selected from: glycolic acid,alpha-acetyl glycolic acid, lactic acid, tartaric acid, alpha-acetyllactic acid, alpha-hydroxy isobutyric acid, salicylic acid, mandelicacid, ortho-acetyl mandelic acid, benzilic acid, ortho-acetyl benzilicacid, malic acid, citric acid, gluconic acid, pyruvic acid, sorbic acidand combinations thereof.

The pH-sensitive transfer indicator may include thymol blue, bromocresol purple, methyl red, cresol red, phenolphthalein, thymolphthalein,or Alizarin yellow R. The pH balancing agent is applied to the web at aplurality of discreet pH balancing agent locations, whereas thepH-sensitive transfer indicator is applied to the web apart from theplurality of discreet pH balancing agent locations. Generally, thepH-sensitive transfer indicator is applied to the web at a plurality ofdiscreet indicator locations whereas the pH balancing agent is appliedto the web apart from the plurality of discreet indicator locations.

Preferably the cellulosic web employed in connection with the inventionis predominantly softwood fiber and/or recycle fiber and includes a wetstrength agent. Suitable wet strength agents may be selected from:aldehyde-containing polyols; aldehyde-containing cationic starch;glyoxal; glutaraldehyde; dialdehydes boric acid carbonate; zirconiumammonium carbonate; glyoxalated polyacrylamide;polyamide-epichlorohydrin; polyamine-epichlorohydrin; urea-formaldehyde;melamine-formaldehyde; polyethyleneimine; and latex emulsions.

In another aspect of the invention there is provided a water solubletriggering agent on the web and a pH-sensitive transfer indicator whichare selected and applied such that the pH-sensitive transfer indicatorundergoes a visually perceivable color change upon contact with waterafter a characteristic time delay of at least about 5 seconds. A timedelay of at least about 10 seconds, 15 seconds or 20 seconds ispreferred in some cases.

In another aspect of the invention the transferable lotion is a lotionemulsion including an anti-microbial agent disposed on the web, thelotion emulsion including a polar emollient and a non-polar emollient aswell as a surfactant composition comprising a non-ionic surfactant. Thelotion emulsion is substantially liquid at room temperature; however,the emollients and surfactant composition are selected such that thelotion emulsion is immobilized on the web in a semi-solid or solid statewhen applied thereto. The lotion emulsion is preferably capable offorming an aqueous gel upon contact with water. The lotion emulsionincludes a polar emollient in an amount of from about 2 percent byweight of the lotion emulsion to about 40 percent by weight of thelotion emulsion. The lotion emulsion may include a poly-hydroxyemollient selected from: propylene glycol; glycol; glycerol; diethyleneglycol; methylene glycol; polypropylene glycol; polyethylene glycol andsorbitol. Further, the lotion emulsion may include a non-polar emollientin an amount of from abut 10 percent by weight of the lotion emulsion toabout 40 percent by weight of the lotion emulsion. Suitable non-polaremollients may be selected from: aromatic or linear esters; Guerbetester; mineral oil; squalane; liquid paraffin, and mixtures thereof.Particular non-polar emollients which are suitable include isopropylmyristate and C₁₂-C₁₅ alkyl benzoate ester (Finsolv TN). Other suitablenon-polar emollients are tri-octyldodecyl-citrate and a mixture ofC₁₂-C₁₅ alkyl benzoate ester and carnation oil.

The surfactant composition may include a non-ionic surfactant and fattyalcohol in the amount of from about 40 percent by weight to about 70percent by weight of the lotion emulsion. Suitable non-ionic surfactantsinclude: PEG-20 methyl glucose sesquistearate; PPG-20 methyl glucoseether; PPG-20 methyl glucose ether distearate; PEG-20 methyl glucosedistearate; PEG-120 methyl glucose dioleate; ethoxylated methyl glucosehaving from about 10 to about 20 repeating ethoxy units per molecule, amixture thereof and the like.

In a preferred embodiment the surfactant composition comprises aco-surfactant in the amount of from about 0.1 percent to about 20percent by weight of the lotion emulsion. The co-surfactant is suitablyselected from C₁₂-C₁₈ fatty alcohols, behenyl alcohol, cetyl alcohol,stearyl alcohol, iso-cetyl alcohol, and iso-stearyl alcohol and mixturesthereof. One preferred co-surfactant is a mixture of cetyl alcohol andstearyl alcohol. Perhaps most preferably, the micro-emulsion issubstantially waterless and capable of forming an aqueous micro-emulsionwhen mixed with water as will be appreciated from the examples appearinghereinafter.

Instead of a lotion emulsion, anti-microbial lotion may be applied inheat sensitive form in another aspect of the invention. In such cases,the transferable lotion disposed on the web includes an emollient, ananti-microbial agent, and a retention/release agent such that the lotionhas a ΔH above about 37° C. of more than 10 calories/gram, a total heatof melting of above about 25 calories/gram, and an onset of meltingtemperature of at least about 30° C. The lotion may further include asurfactant composition in the amount of from about 10 percent to about15 percent by weight of the lotion composition. The surfactant may beselected from methyl glucoside sesquistearate, ethoxylated methylglucoside sesquistearate containing 20 moles of oxyethylene units, orcombinations thereof. A preferred surfactant is a mixture of PEG-20methyl glucose sesquistearate (Glucamate SSE-20) and methyl glucosesesquistearate (Glucate SS). In connection with heat transferablelotions, the lotion composition may include an emollient in the amountof from about 5 percent to about 75 percent by weight of the lotioncomposition. The emollient may include an aromatic ester emollient, afatty alcohol ester of a non-fatty organic acid emollient, or mixturesthereof. Suitable aromatic ester emollients include benzoate esteremollients, selected from C₁₂-C₁₅ alkyl benzoate, stearyl benzoate,octyl dodecyl benzoate, isostearyl benzoate, methyl gluceth-20 benzoate,stearyl ester benzoate, poloxamer 182 dibenzoate, poloxamer 105benzoate, or mixtures thereof. Likewise, fatty alcohol esters of anon-fatty organic acid emollient includes C₁₂-C₁₅ octanoate, forexample. Heat sensitive lotions preferably include a retention/releaseagent in an amount of from about 25 percent to about 95 percent byweight of the lotion composition. Suitable retention/release agentsinclude C₁₂-C₁₈ fatty alcohols. Fatty alcohols may be selected fromdodecanol, tridecanol, tetradecanol, pentadecanol, hexadecanol,heptadecanol, octadecanol, or mixtures thereof. One preferredretention/release agent is a mixture of cetyl alcohol and stearylalcohol. Here again, the lotion composition is preferably substantiallywaterless.

In another aspect of the invention, the transferable lotion compositiondisposed on the web is selected and applied to the web in amounts suchthat the lotion imparts a water absorption rate delay of at least about25 percent. A water absorption rate delay of at least 50 percent istypical. There may be a water absorption rate delay of at least about 75percent or 100 percent imparted to the cellulosic web as will beappreciated from the examples which follow.

While the products of the invention exhibit a substantial absorptionrate delay, the SAT value of the lotion product is substantially thesame as the unlotioned cellulosic web from which the towel is made.Generally, products of the invention have a SAT value of from about 2g/g to about 5 g/g. A SAT value of at least about 3 g/g is preferred asare values of 3.5 g/g, 4 g/g, and 4.5 g/g in some embodiments.

The lotioned products of the invention generally exhibit a WAR value ofat least about 40 seconds and in some cases at least about 50 seconds.Typical products have WAR values of from about 55 to about 75 seconds.WAR values of at least about 100 seconds or at least about 120 secondsmay likewise be observed; especially in products comprising largeamounts of recycle fiber where reduced rates of absorption arebeneficial to product performance. WAR values of from about 75 secondsto about 200 seconds are desirable in some cases.

The transferable lotion of the invention is generally applied to thecellulosic web in an amount of from about 3 percent to about 20 percentby weight, based on the combined weight of the dry web and the lotion.From about 5 percent by weight to about 15 percent by weight is typicaland from about 8 percent by weight to about 10 percent by weight ispreferred in some cases.

The towel of the invention generally has a basis weight of about 15 toabout 65 g/m²; typically of from about 25 to about 50 g/m² andpreferably from about 30 to about 40 g/m². As noted above, the towel ispreferably made with fiber consisting predominantly of softwood and/orrecycle fiber. Typically the web is greater than about 65 percent byweight softwood and/or recycle fiber and preferably at least about 70percent by weight softwood and/or recycle fiber. Softwood and/or recyclefiber content of from about 70 to about 90 percent by weight based onthe dry fiber in the furnish is generally preferred. In someembodiments, it is desirable to have at least 50% by weight of fiberrecycle fiber. At least 60%, at least 70%, at least 80% or at least 90%by weight of recycle fiber may be preferred in still other cases. In onepreferred embodiment, the fiber in the web is 100% by weight recyclefiber. Recycle fiber may be added to the finish in any amount. While anysuitable recycle fiber may be used, recycle fiber with relatively lowlevels of groundwood is preferred in many cases, for example recyclefiber with less than 15% by weight lignin content, or less than 10% byweight lignin content may be preferred depending on the furnish mixtureemployed and the application.

An especially preferred softwood fiber is Douglas fir fiber. Theanti-microbial sheet of the invention may be in the form of a single plytowel having an eight sheet caliper of from about 35 to about 90 mils.

In another aspect of the invention, there is provided an anti-microbialpaper towel with a chromatic transfer indicator including: a) acellulosic web; b) a transferable lotion composition comprising anemollient and anti-microbial agent, the lotion composition beingimmobilized on the cellulosic web in a semi-solid or solid form, whereinthe transferable lotion composition is selected from lotion compositionswhich are transferable upon contact with water or lotion compositionswhich are transferable upon application of heat and is applied to thetowel at an add-on of from about 3 to about 20 weight percent; and c) achromatic transfer indicator which fades after a characteristic timedelay of at least about 5 seconds after contact with the water. In onepreferred embodiment, the transfer indicator comprises a water-solublepolymer which may be selected from the group consisting of polyvinylalcohol, starch, oxygenated hydrocarbons, polyacrylic acid, dextrin, andhydroxypropyl cellulose; alternatively, the transfer indicator comprisesa surfactant. The towel may have an unlotioned basis weight generally offrom about 15 lbs. per 3000 square foot ream to about 45 lbs. per 3000square feet ream. An unlotioned basis weight of from about 20 lbs. per3000 square foot ream to about 40 lbs. for 3000 square foot ream is moretypical, with an unlotioned basis weight of from about 25 lbs. per 3000square foot ream to about 35 lbs. per 3000 square foot ream beingpreferred in many cases. The transferable lotion is applied to the webat an add-on rate of from about 5 to about 15 weight percent; with fromabout 8 to about 10 weight percent being somewhat typical.

Further details and aspects of the invention will become apparent fromthe discussion which follows.

BRIEF DESCRIPTION OF THE DRAWINGS

The patent or application file contains at least one drawing executed incolor. Copies of this patent or patent application publication withcolor drawing(s) will be provided by the Office upon request and paymentof the necessary fee.

FIGS. 1 and 3 are photographs of an unused paper towel treated with a pHbalancing agent (citric acid), and transfer indicator (thymol blue);

FIGS. 2 and 4 are photographs of a paper towel treated with a pHbalancing agent (citric acid), and transfer indicator (thymol blue)after it has been in contact with water;

FIG. 5 is a partial phase diagram of the composition of Example 2showing the phase characteristics of a waterless micro-emulsion; and

FIG. 6 is a partial phase diagram of the composition of Example 2 withwater showing the phase behavior of a mixture of the composition ofExample 2 with water.

DETAILED DESCRIPTION

The invention is described in detail below for purposes of illustrationonly. Modifications within the spirit and scope of the invention, setforth in the appended claims, will be readily apparent to one of skillin the art. As used herein, terminology and abbreviations have theirordinary meaning; for example, “cps” refers to centipoises; g refers tograms, mg refers to milligrams, m² refers to square meters and so forth.

Absorbency of the inventive product is measured with a simple absorbencytester. The simple absorbency tester is a particularly useful apparatusfor measuring the hydrophilicity and absorbency properties of a sampleof tissue, napkin, or towel. In this test a sample of tissue, napkin, ortowel 2.0 inches in diameter is mounted between a top flat plastic coverand a bottom grooved sample plate. The tissue, napkin, or towel sampledisc is held in place by a ⅛ inch wide circumference flange area. Thesample is not compressed by the holder. De-ionized water at 73° F. isintroduced to the sample at the center of the bottom sample platethrough a 1 mm. diameter conduit. This water is at a hydrostatic head ofminus 5 mm. Flow is initiated by a pulse introduced at the start of themeasurement by the instrument mechanism. Water is thus imbibed by thetissue, napkin, or towel sample from this central entrance pointradially outward by capillary action. When the rate of water imbibationdecreases below 0.005 gm water per 5 seconds, the test is terminated.The amount of water removed from the reservoir and absorbed by thesample is weighed and reported as grams of water per square meter ofsample or grams of water per gram of sheet. In practice, an M/K SystemsInc. Gravimetric Absorbency Testing System is used. This is a commercialsystem obtainable from M/K Systems Inc., 12 Garden Street, Danvers,Mass., 01923. WAC or water absorbent capacity also referred to as SAT isactually determined by the instrument itself. WAC is defined as thepoint where the weight versus time graph has a “zero” slope, i.e., thesample has stopped absorbing. The termination criteria for a test areexpressed in maximum change in water weight absorbed over a fixed timeperiod. This is basically an estimate of zero slope on the weight versustime graph. The program uses a change of 0.005 g over a 5 second timeinterval as termination criteria; unless “Slow SAT” is specified inwhich case the cut off criteria is 1 mg in 20 seconds.

Water absorbency rate or WAR, is measured in seconds and is the time ittakes for a sample to absorb a 0.1 gram droplet of water disposed on itssurface by way of an automated syringe. The test specimens arepreferably conditioned at 23° C.±1° C. (73.4±1.8° F.) at 50% relativehumidity. For each sample, 4 3×3 inch test specimens are prepared. Eachspecimen is placed in a sample holder such that a high intensity lamp isdirected toward the specimen. 0.1 ml of water is deposited on thespecimen surface and a stop watch is started. When the water isabsorbed, as indicated by lack of further reflection of light from thedrop, the stopwatch is stopped and the time recorded to the nearest 0.1seconds. The procedure is repeated for each specimen and the resultsaveraged for the sample. WAR is measured in accordance with TAPPI methodT-432 om-99.

The water absorption rate delay in percent is calculated from the WARvalues of the unlotioned cellulosic web and lotioned sheet product ofthe invention as follows:Absorption rate delay=(WAR value of lotioned cellulosic sheet−WAR valueof unlotioned cellulosic web)÷(WAR value of unlotioned cellulosicweb)×100%

“Aqueous gel” refers to viscous lotion/water compositions typicallyhaving a room temperature viscosity of above about 500 cps at roomtemperature and typically above about 1000 cps at room temperature.Preferred lotion compositions form gels of more than 1500 cps at roomtemperature as is seen in Table 2 below.

“Basis weight”, BWT, bwt and so forth is expressed in grams per squaremeter or pounds per 3000 square foot ream of product as is indicated.

The term “cellulosic”, “cellulosic sheet” and the like is meant toinclude any product incorporating papermaking fiber having cellulose asa major constituent. “Papermaking fibers” include virgin pulps orrecycle (secondary) cellulosic fibers or fiber mixes comprisingcellulosic fibers. Fibers suitable for making the webs of this inventioninclude fibers such as those obtained from deciduous and coniferoustrees, including softwood fibers, such as northern and southern softwoodkraft fibers; hardwood fibers, such as eucalyptus, maple, birch, aspen,or the like as well as nonwood cellulosic fibers. Papermaking fibers canbe liberated from their source material by any one of a number ofchemical pulping processes familiar to one experienced in the artincluding sulfate, sulfite, polysulfide, soda pulping, etc. The pulp canbe bleached if desired by chemical means including the use of chlorine,chlorine dioxide, oxygen, alkaline peroxide and so forth. The productsof the present invention may comprise a blend of conventional fibers(whether derived from virgin pulp or recycle sources) and highcoarseness lignin-rich tubular fibers, such as bleached chemicalthermomechanical pulp (BCTMP). “Furnishes” and like terminology refersto aqueous compositions including papermaking fibers, optionally wetstrength resins, debonders and the like for making paper products.

Preferably, the fiber in the towel products of the invention consistspredominantly (more than 50% by weight of fiber based on fiber content)of softwood (SW) fiber such as Douglas fir. Southern Softwood Kraft(SSWK) is also a preferred fiber. Softwood fibers provide strength tothe product; Southern softwoods are generally preferred for towel of theinvention; however thin and flexible Northern softwood may be used insome fiber mixtures.

Percent means weight percent unless otherwise indicated and refers toweight percent without water unless the inclusion of the water weight isexpressly indicated. Weight percent softwood fiber and like terminologyor expressions refer to the weight percent of softwood fiber based onfiber content of a product or composition only, exclusive of otheringredients.

Room temperature refers to a temperature of from about 20° C. to about25° C.

Characteristic time delay of the transfer signal of a towel product ofthe invention is determined by placing a sample of towel on the surfaceof a bath of deionized water (or any source sufficient to saturate thesample) and recording the time delay between placing the towel on thebath (t=0) and a visually observable color change (t=characteristic timedelay). Time delay is expressed in seconds.

Dry tensile strengths (MD and CD), stretch, ratios thereof, modulus,break modulus, stress and strain are measured with a standard Instrontest device or other suitable elongation tensile tester which may beconfigured in various ways, typically using 3 or 1 inch wide strips oftissue or towel, conditioned in an atmosphere of 23°±1° C. (73.4°±1° F.)at 50% relative humidity for 2 hours. The tensile test is run at acrosshead speed of 2 in/min. Break modulus is expressed in grams/3inches/% strain. % strain is dimensionless and need not be specified.

Tensile ratios are simply ratios of the values determined by way of theforegoing methods. Unless otherwise specified, a tensile property is adry sheet property.

The wet tensile of the tissue of the present invention is measured usinga three-inch wide strip of tissue that is folded into a loop, clamped ina special fixture termed a Finch Cup, then immersed in a water. TheFinch Cup, which is available from the Thwing-Albert Instrument Companyof Philadelphia, Pa., is mounted onto a tensile tester equipped with a2.0 pound load cell with the flange of the Finch Cup clamped by thetester's lower jaw and the ends of tissue loop clamped into the upperjaw of the tensile tester. The sample is immersed in water that has beenadjusted to a pH of 7.0±0.1 and the tensile is tested after a 5 secondimmersion time.

“Waterless”, “substantially waterless” and like terminology refers tocompositions which include generally less than about 10% by weightwater. In cases where water is present at all, water is preferably notadded as such, but is contained in other ingredients.

In some preferred embodiments of the present invention, the lotioncomposition is a “cold,” lotion such as the lotions described in U.S.Pat. No. 7,169,400 to Luu et al., incorporated herein by reference inits entirety. “Cold” lotions refer to lotions that are substantiallyliquid at room temperature and can be applied as such to substrates. Dueto the liquid state of the “cold” lotions at room temperature, they donot require heating or melting equipment and can be applied to thesubstrates by several available technologies such as spraying, printing,coating, extrusion or other techniques.

The cold lotion used in the present invention contains a micro-emulsioncomposition containing predominantly an emollient composition and asurfactant composition. The small particle size of the micro-emulsionincreases the surface area of its constituents so it contributes to theutility of the present composition in increasing the interaction betweenthe emollient and the skin surface; a desirable property for restoringthe oil layer of the skin. Preferably, the micro-emulsion compositioncontains an external continuous non-polar or polar emollient, aninternal discontinuous polar or non-polar emollient, a surfactant and amixture of fatty alcohol co-surfactants. The lotion composition may alsocontain optional ingredients, including typical cosmetic additives,preservatives, plant extracts, fragrances, and medicinal agents. Anysuitable combination or proportion of ingredients which produces amicro-emulsion can be used.

An important aspect of the cold lotion employed is when the liquidlotion contacts the fibers or non-woven substrate, it undergoes anin-situ phase change from liquid to immobilized semi-solid or solidform. This phase change of the lotion results when the substrate websurface fibers absorb the continuous outer phase of the micro-emulsion,which may be a non-polar or polar-emollient. Subsequently, the percentof the outer phase of the micro-emulsion within the composition isreduced, resulting in increase in the percent of the internal phase ofthe micro-emulsion and shuft of the original lotion composition frompoint A (liquid micro-emulsion) to points B or C (semi-solid state),which are located outside of the micro emulsion region (see FIG. 5). Theimmobilized antimicrobial lotion is restorable to transferable form uponcontact with water and is capable of forming an aqueous gel. Thecompositions of the present invention are preferably chosen to liewithin the micro-emulsion region of a given formulation. Allpercentages, ratios, and proportions of the ingredients within thecompositions of the present invention are determined by themicro-emulsion region of a ternary phase diagram of the polaremollient/non-polar emollient/co-surfactant/non-ionic surfactantformulations (PE/NPE/COS/NIS). Outside of the micro-emulsion region onthe low percent side of the polar or non-polar emollients, a semi-solidor solid region is preferably present. A micro-emulsion isthermodynamically stable and is essentially transparent in the visibleregion of the spectrum, which typically indicates that particle sizediameter is preferably less than about 0.1 micron, or so. When theparticle size diameter is greater than about 3,200 A (about 0.32micron), the liquid is no longer considered a micro-emulsion but is anemulsion which can often appear turbid and be thermodynamicallyunstable. The micelle structure of a micro-emulsion is either a “direct”type (head out/tail in) or an “inverse” type (head in/tail out). Theliquid micro-emulsion increases the surface area of the lipophilicconstituent so it contributes significantly to the utility of thepresent composition in neat form. Fluidity on the skin surface, smallparticle size, high surface area and high hydrophilic character, arehighly desirable properties for cleansing purposes either when thesubstrate is used by itself or when lotioned products are rewet withwater. Any combination or proportion of these ingredients which producesa micro-emulsion can be used.

A hot lotion composition used in connection with the present inventionis chosen such that its ΔH of above about 37° C. is above about 10calories/gram, ΔH of below about 37° C. is above about 15 calories/gram,ΔH total (total energy to melt) of above about 37° C. is above about 25calories/gram. Further, the retention/release agent is preferablyselected to have a melting point substantially higher than about roomtemperature but lower than about 65° C., such that the lotion onset ofmelting temperature is within the range of from about 30° C. to about45° C. This enables the lotion composition to maintain a substantiallysolid state at about room temperature and partially melted state athuman skin temperature.

It should be noted that for purposes of this description, thetemperature of human skin is between about 30° C. to about 37° C. androom temperature is between about 20° C. to about 25° C.

An important aspect of a hot lotion used is that it is partially meltedby body heat to enable transfer to the skin of partially liquefied andpartially solid emollient(s), particles of retention/release agent andother ingredients. The partial melting of the lotion is important,because when the lotion is completely melted to liquid by body heat itis perceived as too greasy, and when a lotion is not sufficiently meltedby body heat, it would not spread easily on the skin. At least a portionof the partially melted lotion resolidifies on the skin to form a smoothand moisturizing layer. Further details as to suitable hot lotioncompositions are found in U.S. Pat. No. 5,871,763, the disclosure ofwhich is incorporated herein by reference in its entirety.

Optionally included in the anti-microbial lotions are suitableanti-viral agents including those effective against, or at leastretardant toward Corona virus, Picorna virus, Rhino virus, Herpessimplex, Herpes genitalis, Herpes labialis, Respiratory Syncytial Virus(RSV), Para influenza, Cytomegalovirus, Adenovirus, Condyloma andcertain synergistic disease states that can involve a virus and aprotozoa or a virus and any unfriendly enzymes, e.g., protease, lipaseand amylase, that cause a compromised skin as a precursor state for aviral infection to occur. Specific anti-viral agents suitable for use inthe lotions include bioflavonoids such as hesperitin, naringin, catechinand certain selected amino acids of leguminous origin such asL-canavanine and an analog of L-arginine; dicarboxylic acids such asmalonic, glutaric, citric, succinic, and diglycolic acids; alpha hydroxycarboxylic acid such as D-galacturonic acid from Sterculia urens; neemseed oil (Azadirachta indica) in its un-denatured form; sandalwood oil(Santalum album L.) in its un-denatured form. Optionally, the anti-viralagent could be admixed with at most about 50% by weight of theanti-viral agent of a protease inhibitor such as zinc oxide or othersuitable zinc salt.

The cold or hot lotion composition can include other optional componentstypically present in lotions of this type. These optional componentsinclude a botanical extract, such as aloe extract, avocado oil, basilextract, sesame oil, olive oil, jojoba oil, chamomile extract,eucalyptus extract, peppermint extract, as well as animal oils such asemu oil, cod liver oil, orange roughy oil, mink oil, and the like.

The lotion of the present invention can also optionally include ahumectant. Humectants are hygroscopic materials with a two-foldmoisturizing action including water retention and water absorption.Humectants prevent the loss of moisture from skin and help to attractmoisture from the environment. Preferred humectants include glycerol,hydrolyzed silk, ammonium lactate, hydroxypropyltrimonium hydrolyzedsilk, hydroxypropyl chitosan, hydroxypropyltrimonium hydrolyzed wheatprotein, lactamidopropyltrimonium chloride, and ethyl ester ofhydrolyzed silk. The botanical extract, animal oil or humectant ispreferably present in an amount of less than about 3% when used in thebase formulation of the lotion. Further optional components include askin refreshing agent such as encapsulated water in oil, eucalyptus oil,and menthol oil. All of these optional materials are well known in theart as additives for such formulations and can be employed inappropriate amounts in the lotion compositions of the present inventionby those skilled in the art.

The lotion can optionally include a fragrance. The fragrance can bepresent in an amount of from 0.01% to about 2%. Suitable fragranceincludes volatile aromatic esters, non-aromatic esters, aromaticaldehydes, non-aromatic aldehydes, aromatic alcohols, non-aromaticalcohols, heterocyclic aroma chemicals, and natural floral fragrances,such as blossom, carnation, gardenia, geranium, iris, hawthorne,hyacinth and jasmine.

The lotion can also optionally include natural or synthetic powder liketalc, mica, boron nitride, silicone, or mixtures thereof.

The towel web of the present invention can be any suitable cellulosicsubstrate web, optionally wet-strengthened, and optionally includingsynthetic fibrous material such as melt-blown polyethylene,polypropylene, copolymers of polyethylene. The substrate also may beembossed.

Wet strength agents which may be added include temporary as well aspermanent wet strength agents. Suitable wet strength agents includeglyoxal; glutaraldehyde; uncharged chemical moieties selected from agroup consisting of dialdehydes, aldehyde-containing polyols, unchargedaldehyde-containing polymers, and cyclic ureas and mixtures thereof, andaldehyde-containing cationic starch; mixtures of polyvinyl alcohol andsalts of multivalent anions, such as boric acid or zirconium ammoniumcarbonates; glyoxalated polyacrylamide; polyamide-epichlorohydrin;polyamine-epichlorohydrin; urea-formaldehyde; melamine-formaldehyde;polyethyleneimine; and latex emulsions.

The present invention includes a web of cellulosic fibers treated on atleast one side thereof, preferably in an amount of from about 0.1% toabout 25%, more preferably from about 0.5% to about 20%, by weight ofthe dried fiber web with an ant-microbial lotion.

The cellulosic substrate can be prepared according to conventionalprocesses (including TAD, CWP and variants thereof) known to thoseskilled in the art. In many cases, the fabric creping techniquesrevealed in the following co-pending applications will be especiallysuitable: U.S. patent application Ser. No. 11/678,669, entitled “Methodof Controlling Adhesive Build-Up on a Yankee Dryer; U.S. patentapplication Ser. No. 11/451,112 (Publication No. US 2006-0289133), filedJun. 12, 2006, entitled “Fabric-Creped Sheet for Dispensers”; U.S. Ser.No. 11/451,111, filed Jun. 12, 2006 (Publication No. US 2006-0289134),entitled “Method of Making Fabric-creped Sheet for Dispensers”; U.S.patent application Ser. No. 11/402,609 (Publication No. US2006-0237154), filed Apr. 12, 2006, entitled “Multi-Ply Paper Towel WithAbsorbent Core”; U.S. patent application Ser. No. 11/151,761, filed Jun.14, 2005 (Publication No. US 2005/0279471), entitled “High SolidsFabric-crepe Process for Producing Absorbent Sheet with In-FabricDrying”; U.S. application Ser. No. 11/108,458, filed Apr. 18, 2005(Publication No. US 2005-0241787), entitled “Fabric-Crepe and In FabricDrying Process for Producing Absorbent Sheet”; U.S. application Ser. No.11/108,375, filed Apr. 18, 2005 (Publication No. US 2005-0217814),entitled “Fabric-crepe/Draw Process for Producing Absorbent Sheet”; U.S.application Ser. No. 11/104,014, filed Apr. 12, 2005 (Publication No. US2005-0241786), entitled “Wet-Pressed Tissue and Towel Products WithElevated CD Stretch and Low Tensile Ratios Made With a High SolidsFabric-Crepe Process”; U.S. application Ser. No. 10/679,862 (PublicationNo. US 2004-0238135), filed Oct. 6, 2003, entitled “Fabric-crepe Processfor Making Absorbent Sheet”; U.S. Provisional Patent Application Ser.No. 60/903,789, filed Feb. 27, 2007, entitled “Fabric Crepe Process WithProlonged Production Cycle”; U.S. Provisional Patent Application Ser.No. 60/850,467, filed Oct. 10, 2006, entitled “Absorbent Sheet HavingLyocell Microfiber Network”; GP-06-8-1); U.S. Provisional PatentApplication Ser. No. 60/808,863, filed May 26, 2006, entitled“Fabric-creped Absorbent Sheet with Variable Local Basis Weight”; andU.S. Provisional Patent Application Ser. No. 60/784,228, filed Mar. 21,2006, entitled “Absorbent Sheet Having Lyocell Microfiber Network”. Theapplications referred to immediately above are particularly relevant tothe selection of machinery, materials, processing conditions and soforth as to fabric creped products of the present invention and thedisclosures of these applications are incorporated herein by reference.

The methodology employed for fabric creped substrates includes: a)compactively dewatering a papermaking furnish to form a nascent webhaving an apparently random distribution of papenraking fiber; b)applying the dewatered web having the apparently random fiberdistribution to a translating transfer surface moving at a first speed;and c) fabric-creping the web from the transfer surface at a consistencyof from about 30% to about 60%, the creping step occurring underpressure in a fabric creping nip defined between the transfer surfaceand the creping fabric wherein the fabric is traveling at a second speedslower than the speed of said transfer surface, the fabric pattern, nipparameters, velocity delta and web consistency being selected such thatthe web is creped from the transfer surface and redistributed on thecreping fabric to form a web with an optionally drawable reticulumhaving a plurality of interconnected regions of different local basisweights including at least (i) a plurality of fiber-enriched regions ofhigh local basis weight, interconnected by way of (ii) a plurality ofoptionally elongated densified regions of compressed papermaking fibers,the densified regions having relatively low local basis weight andoptionally being generally oriented along the machine direction (MD) ofthe sheet. In one embodiment, the elongated densified regions arefurther characterized by an MD/CD aspect ratio of at least 1.5.

A preferred towel web is a fabric-creped towel web as is used in Example18. Lotion can be applied to the substrate according to conventionalapplication methods known to those skilled in the art.

Example 1

Towels of the invention include a time-delay chromatic transferindicator to help promote lotion transfer to the skin by encouragingprolonged contact with the skin. Typically, the towel includes atransfer indictor system with an invisible part and a visible part whichmay be applied to a towel with a multi-layer glue applicator utilized inconnection with a 3 or 4 roll embossing station. The invisible part ofthe system (which may be incorporated in a lotion formula) istransferred to the towel, either on a separate sheet for 2-ply productor are side-by-side on the same sheet for a 1-ply product but the“trigger”, for example, of organic acid is kept separate from thetransfer indicator, that is, the trigger is suitably disposed in aplurality of locations apart from a plurality of locations where thetransfer indicator is located.

The color of a visible part of the transfer indicator system should bered, purple, green or blue and contains a pH sensitive material. The pHof these colorants is either acidic (1-5) or basic (7.5-14) and they areeither in aqueous solution with or without solvent or encapsulated. Thecolorants may be either food contact or non-food contact chemicals.

When users of the towel dry their wetted hands, time for disappearanceof the “visible part” of the upper indicator system can be an effectivetool to communicate to them that the duration of hand rubbing was in aproper manner, about 15 seconds or more as is suitable for the lotion.This encouraged vigorous wiping action, which has been shown to removefurther microorganisms and contamination after hand washing, and also toimprove transferring lotion active agents to skin. Increasing ordecreasing the wicking time and the chemical concentration of theinvisible part, as well as from a specific graphic design of the visiblepart, can control the towel response.

In the attached FIGS. 1 through 4, the system of “thymol blue/citricacid” is printed on a hand towel basesheet. The visible blue dots arethymol blue (pH=8 to 9.5), they are surrounded by the invisible dots ofcitric acid (pH=2). When the prototype is wetted with city water, thewetted part of the hand towel becomes colorless with or without wipingaction.

The enhanced towel of the invention is preferably dispensed in atouchless dispenser or as multifold towel in a hands-free dispenser.

The chromatic transfer indicator is in many preferred cases a fadingdesign or graphic which is provided by any suitable means such as pHsensitive inks, water soluble inks, colored particles, hydratable salts;or another colorant which fades substantially upon contact with tapwater. It will be appreciated from the foregoing that the indicatorsystems preferably includes a visible part and an invisible part asfollows:

1) Visible Part: The color of this part should be red, purple, green orblue and contains pH sensitive materials. The pH of these colorants iseither acidic (1-5) or basic (7.5-14), and they are either in aqueoussolution with or without solvent or encapsulated. Furthermore, thesechemicals are either food on non-food contact materials. The colorant ofthe visible part is printed on the surface of the paper, plastic film,or non-woven substrate with a specific, selected design to demonstratethe benefit of the product. The selected design can be a word, sentence,graphic or special pattern, alone or in combination with an embossingdesign.

2) Invisible Part: The function of this part, when the product is wettedwith water, is providing the necessary pH for changing the visible colorto a colorless or a lighter color. The chemical of the invisible partmight include non-toxic organic acid (i.e., citric acid, lactic acid,glycolic acid, etc.), inorganic acid or a buffer solution, providing itspH is in the range of 5.5 to 7. The invisible material is usuallycolorless and water-soluble and printed on the surface of the substrate,either on a separate sheet or side by side on the same sheet but not incontact with the visible material.

The desired time for disappearance of the visible part can be controlledby increasing or decreasing the wicking time of the invisible part byblending it with lotion, hydrophobic or hydrophilic surfactant, orwater-soluble polymer such as PVOH, polyacrylic acid, starch, dextrin,hydroxypropyl cellulose, etc. Increasing or decreasing the chemicalconcentration or the distance between visible and invisible material inthe pattern design is also a simple method in providing an appropriatedisappearance time of the visible part of the disappearing graphic.

The transfer indicator can be applied on a hand-washing towel, kid'stowel, guest towel, etc., and it can also be applied as a WettingIndicator (WI) for diapers. In the attached FIGS. 1 to 4, the Thymolblue/acid citric system is printed on a hand towel. The visible bluedots are thymol blue (pH=8-9.5); they are surrounded by invisible dotsof citric acid (pH=2) of like size and frequency. When the prototype isrewetted with city water (FIGS. 2, 4), the wetting part of the handtowel becomes colorless with or without wiping action. FIGS. 1-4 showthat the “thymol blue-citric acid” system as well as the pattern designare the key to contributing to the achievement of the desired wipingtime for the use of transferring anti-microbial lotion, for example.

Examples 2-8

Formulations of the waterless lotion were prepared in which, thecomponents, their ratios and the conditions selected to providemicro-emulsion subject to in-situ phase change upon contact with acellulosic substrate were varied as shown in the following Examples.

In preparing each formulation the following, a general procedure wasused. The polar phase propylene glycol was mixed with surfactant andco-surfactant in a heated container at about 60° C. to about 70° C.until the chemicals were completely melted. The non-polar oil phase wasadded to the mixture with moderate agitation for about 10 minutes, andthen cooled to room temperature. At this point the lotion was in clearliquid form and ready to apply to the substrate. The micro-emulsionformed spontaneously without the need for a high shear mechanical deviceand is stable indefinitely.

Examples 2 to 8 were prepared in accordance with U.S. Pat. No. 7,169,400to Luu et al., the disclosure of which is incorporated herein byreference. These lotion formulas were liquid at room temperature,transparent, very stable and accordingly the lotion ingredient ratioswere inside the micro-emulsion region of phase diagrams such as FIG. 5which is a partial phase diagram of the composition of Example 2.Surprisingly, the lotion of the present invention is characterized ashaving a good hand-feel perception and non-greasy hand-feel, which isthought to be due to the particle size of the micro-emulsion being toosmall to be detected in the oil phase by the fingertips.

TABLE 1 Ex. 2 Ex. 3 Ex. 4 Ex. 5 Ex. 6 Ex. 7 Ex. 8 Ingredients (%) (%)(%) (%) (%) (%) (%) Propylene glycol 35 35 5 15 15 30 35 Finsolv TN⁽¹⁾12.5 0 16 0 30 15 0 Carnation oil⁽²⁾ 0 0 0 0 0 0 12.5 Isopropylmyristate 0 15 0 30 0 0 0 Lambert CE 2000⁽³⁾ 0 0 4 0 0 0 0 Myristylalcohol(C₁₄) 12.5 15 0 0 0 0 12.5 Kalcol 1618⁽⁴⁾ 0 0 7.5 0 5.5 5.5 0Glucam P-20 0 0 67.5 0 49.5 49.5 0 Distearate⁽⁵⁾ Glucamate SSE-20⁽⁶⁾ 4035 0 55 0 0 40 ⁽¹⁾Finsolv TN: C₁₂-C₁₅ alkyl benzoate ester from FinetexInc. ⁽²⁾Carnation: Mineral oil from Witco Corp. ⁽³⁾Lambert CT 2000 -tri-octyldodecyl-citrate (Guerbet ester) from Lambert Technologies.⁽⁴⁾Kalcol 1618: Mixture 50/50 of cetyl alcohol (C16) and stearyl alcohol(C18) from Kao Corp. ⁽⁵⁾Glucan P-20 Distearate: PEG-20 methyl glucosedistearate from Amer-chol. ⁽⁶⁾Glucamate SSE-20: PEG-20 methyl glucosesesquistearate from Amer-chol.

Example 9

The lotion prepared in Example 2 was applied to a tissue basesheet at a5% add-on level, then converted to a two ply tissue product. The productwas tested for the amount of lotion transferred to the skin. The resultswere compared with commercially available lotioned tissues by comparingthe light reflection of cold lotion residual on glass relative to thatfrom two other products. The scattering of light caused by lotionsmeared onto the glass microscope slide was measured by using theUV/visible spectrophotometer in the wavelength region from 700 nm to 400nm. Lotion was transferred to the slide by holding it between two layersof lotioned tissue for 30 seconds and then rubbing the tissue over theslide 20 times in 15 seconds. The lotion smeared glass slide was placedin the sample beam of a double beam UV/visible spectrometer to measurethe light scattering. The results show that scattering of light causedby lotion smeared onto the slide rubbed with the tissue treated with thelotion in Example 1, looked identical to the control (untreated tissue).However, the two commercially available lotioned facial tissue productstested produced a significant amount of light scattering compared to thelotioned tissue of the present invention. In fact, the containers forthese commercial products specifically state “not recommended forcleaning eyeglasses.” In addition, from the lab test result, the amountof lotion transferred by the lotioned substrate of the present inventionto the skin was measured to be about 4.2 mg/cm².

The lotioned substrate product of the present invention was able totransfer lotion to the skin for enhancing skin care benefits, while alsobeing able to “wipe eyeglasses and still maintain clear vision.” Theseproperties of the present invention represent significant advantagesover the lotioned facial tissues of the prior art.

The waterless emulsion compositions of the present invention havenumerous attributes which make them particularly suitable for papertowels. For one, the waterless micro-emulsions form low viscosityaqueous micro-emulsions with relatively small amounts of water such thatan immobilized lotion on the substrate is restorable to readilytransferable form when wetted or mixed with water. Thus, when contactedwith wet hands of a paper towel user, for example, the lotion is readilytransferred from the towel to the skin of a user.

Another unique characteristic of the invention is that the lotionemulsions are capable of forming viscous gels with water as the amountof water mixed with the lotion is increased. Gels are generally moreglutinous than liquids, thus being more desirable as hand lotions.

Details as to these characteristics appear in Examples 10-17 below.

Examples 10-17

The composition of Example 1 was mixed with water and tested forviscosity using a Brookfield Digital Viscometer at 73° F. Examples 10,11, 12 and 17 were tested with a No. 2 spindle, while Examples, 13, 14,15 and 16 were tested with a No. 5 spindle. Details as to compositionand test conditions appear in Table 2 below.

TABLE 2 Aqueous Phasing Properties Appearance Example #/ Spindle SpeedViscosity and Description # (RPM) (cps) Properties 10/100% Lotion 2 50182 Clear Example #1 Liquid 11/95% Lotion 2 50 218 Clear Example #1 + 5%Liquid Water 12/90% Lotion 2 50 348 Clear Example #1 + 10% Liquid Water13/85% Lotion 5 10 4,600 Viscous Example #1 + 15% gel Water 14/80%Lotion 5 10 22,000 (2)  Elastic Example #1 + 20% gel Water 15/70% Lotion5 10 13,000 (2&3) Crystalline Example #1 + 30% gel Water 16/50% Lotion 510 3,500 Viscous Example #1 + 50% turbid Water gel 17/20% Lotion 2 50140 Turbid Example #1 + 80% emulsion Water

It is seen in Table 2 that the water/emulsion mixtures remained amicro-emulsion up to a water concentration of between 10% and 15% byweight of the composition (Examples 10-13). At 15% water, the lotionemulsion turned into a viscous gel, which became even more viscous asadditional water was added. At 20% water, the composition was an elasticgel having a viscosity of 22,000 cps, making viscosity measurementdifficult. At 30% water (Example 15), the gel exhibited some opacity andappeared to have some crystalline structure appearing almost brittle.Due to the difficulty of viscosity measurement as well as the elasticand adhesive properties of the elastic gel of Example 14, the actualdifference in viscosity between Examples 14, 15 may be less thanindicated in Table 2.

At 50% by weight water, viscosity fell off dramatically and thecomposition appeared to be a viscous, turbid gel which was somewhattranslucent. While the viscosities of Examples 13 and 16 were similar,the composition of Example 15 exhibited considerably more turbidity. At80% water, viscosity was low again; however, the composition was nolonger clear and appeared to be an emulsion which was somewhat turbid.

The phase behaviors of the mixtures of Table 2 are illustrated in thepartial phase diagram of FIG. 6, where it is seen that Examples 10, 11and 12 are within the micro-emulsion region of the phase diagram.Examples 13, 14, 15 and 16 are in “semi solid” form, while Example 17 isa two-phase liquid.

Example 18 and Comparative Example A

Still further features of the invention which are highly desirableinclude WAR delay which promotes lotion transfer to the skin andanti-microbial action of paper towel. These features are appreciatedfrom the discussion which follows.

Towel basesheet was prepared using 100% Douglas Fir Kraft fiber by wayof a fabric crepe/Yankee dry process of the class disclosed inco-pending Provisional Application No. 60/693,699, entitled“Fabric-Creped Sheet for Dispensers”, filed Jun. 24, 2005, the relevantdisclosure of which is incorporated herein by reference in its entirety.To the basesheet, lotion was applied in 1″ bands along the machinedirection (alternating with 1″ bands of unlotioned towel) using aDynatec™ applicator of the class seen in U.S. Pat. Nos. 5,904,298;5,902,540; and 5,882,573, the disclosures of which are incorporatedherein by reference. The lotion formulation of Example 1 was used,containing additionally 2% by weight lotion triclosan anti-microbialcompound, 2,4,4′-trichloro-2′-hydroxy diphenyl ether. Further detailsappear in Table 3 below.

The towel was treated for anti-microbial properties by placing a wettedspecimen disk of towel in a Petri dish on inoculated agar. Theanti-microbial properties are termed “negative” if microbe contaminationis observed on or at the towel after incubation and “positive” if a“ring” around the test specimen is observed, indicating that microbegrowth was inhibited by the towel.

Results of anti-microbial testing also appear in Table 3.

TABLE 3 Anti-microbial and Towel Properties Example A Example 18Properties No Lotion Lotioned Anti-microbial Properties: Staphylococcusaureus Negative Positive E. coli Negative Positive Salmonella spsNegative Positive Physical Properties: Add on rate (% of product weight)0% 8 to 10% Basis Weight (lbs/rm) 22.2 23.5 Caliper (mils/8 sheets) 46.046.1 Dry MD Tensile (g/3″) 6531.2 5528.9 Dry CD Tensile (g/3″) 3912.03435.1 MD Stretch (%) 7.4 7.7 CD Stretch (%) 3.3 3.7 Wet MD CuredTensile (g/3″) 1976.1 2040.1 (Finch) Wet CD Cured Tensile (g/3″) 1041.01122.1 (Finch) WAR (seconds) (TAPPI) 34.3 67.6 MacBeth 3100 Brightness(%) 77.5 75.5 UV Excluded Opacity (%) 60.2 56.6 SAT Capacity(g/m{circumflex over ( )}2) 125.1 123.0 SAT Time (seconds) 643.7 823.6GM Break Modulus 1025.2 829.0

It is seen in Table 3 that the anti-microbial lotion was effectiveagainst staphylococcus aureous, E. coli and salmonella sps.

It is also seen that, with the absorbent capacity (SAT) of the controland the lotioned towel remained substantially the same, WAR times, orabsorption rates were considerably lengthened, perhaps due to gelblockage; consistent with the data in Table 2 above. Higher WAR valuesare generally not desired; however, the glutinous gel feel and initial“wetness” experienced by a towel user is a positive consequence,offsetting lower measured absorption rates and encouraging more wipingaction so the anti-microbial lotion is more effective in preventing orameliorating contamination. The apparent gel blockage also appeared toincrease CD wet tensile, a common source of towel failure.

Examples 19-23

The lotion compositions in the following examples comprise a base lotionwith and without a pH balancing agent. Examples 19 and 20 arecomparative and contain no pH balancing agent, and Examples 21-23 relateto lotion compositions combined with a pH balancing agent. Furtherdetail is seen in U.S. Pat. No. 6,352,700, the disclosure of which isincorporated herein in its entirety.

The lotions in Examples 21-23 were prepared according to the followingprocedure: the base lotion ingredients, i.e., emollient(s), release andretention agent and surfactants were mixed together and heated to 75° C.until the mixture was completely melted. Note lotion compositioncomponents in Table 7. The lotion composition mixture was maintained at75° C. for about 15 minutes with moderate agitation. The pH balancingcompound was then added, using high agitation, until the compound wascompletely melted and blended. The pH value for each lotion wasdetermined by emulsifying 0.276 g of solid lotion (equivalent to thelotion amount contained in 5 sheets of 15% lotionized tissue) in 20 mltap water (pH=8.65) at 23° C. The emulsion was shaken for 5 minutesbefore measuring pH using a standard calibrated pH meter.

TABLE 4 pH Balanced Lotions Exam- Example Example Example Example pleChemicals 19 (%) 20 (%) 21 (%) 22 (%) 23 (%) Finsoly 30 35 35 30 30TN-C12-C15 alkyl benzoate Crodacol 57 65 63 56 55 CS 50 (Cetearylalcohol) Clucate SS 3 0 0 3 3 (methyl glucose sesquistearate) Glucamate10 0 0 10 10 SSE-20 (PEG-20 methyl glucose sesquistearate) Glycolic acid0 0 2 1 0 Lactic acid 0 0 0 0 2 pH 7.8 7.2 4.6 4.9 5.3

While the invention has been described in connection with numerousexamples, modifications to those examples within the spirit and scope ofthe invention will be readily apparent to those of skill in the art. Inview of the foregoing discussion, relevant knowledge in the art andreferences including co-pending applications discussed above, therelevant disclosures of which are all incorporated herein by reference,and further description is deemed unnecessary.

1. An antimicrobial paper towel with a chromatic transfer indicatorcomprising: a) a cellulosic web; b) a transferable lotion compositioncomprising an emollient and anti-microbial agent, the lotion compositionbeing immobilized on the cellulosic web in a semi-solid or solid formand selected and applied in amounts such that it imparts a waterabsorption rate delay of at least about 25% to the cellulosic web,wherein the transferable lotion composition is selected from lotioncompositions which are transferable upon contact with water or lotioncompositions which are transferable upon application of heat; c) a watersoluble pH balancing agent disposed on the web at a plurality ofdiscrete pH balancing agent locations; and d) a pH-sensitive transferindicator disposed on the web at a plurality of discrete indicatorlocations which are apart from the pH balancing agent locations, whereinthe pH-sensitive transfer indicator is chromatically responsive to thepH balancing agent in aqueous form; wherein the pH balancing agent andthe pH-sensitive transfer indicator are selected and applied to the websuch that the pH-sensitive transfer indicator undergoes a gradual colorchange upon contact of the paper towel with water to indicate effectivetransfer of the lotion, wherein the initiation of said color change isdetermined by the wicking time of the pH balancing agent.
 2. Theanti-microbial paper towel according to claim 1, wherein the lotioncomposition comprises from about 0.01% to about 10% by weightanti-microbial agent.
 3. The anti-microbial paper towel according toclaim 1, wherein the lotion composition comprises from about 0.05% toabout 5% by weight anti-microbial agent.
 4. The anti-microbial papertowel according to claim 1, comprising an anti-microbial agent selectedfrom: 2,4,4′-trichloro-2′-hydroxydiphenyl ether;3,4,4′-trichlorocarbanilide;3,4,4′-trifluoromethyl-4,4′-d-ichlorocarbanilide;5-chloro-2-methyl-4-isothiazolin-3-one; iodopropynlbutylcarbamate;8-hydroxyquinoline; 8-hydroxyquinoline citrate; 8-hydroxyquinolinesulfate; 4-chloro-3,5-xylenol; 2-bromo-2-nitropropane-1,3-diol;diazolidinyl urea; butoconazole; nystatin; terconazole; nitrofurantoin;phenazopyridine; acyclovir; clortrimazole; chloroxylenol; chlorhexidine;chlorhexidine gluconate; miconazole; terconazole; butylparaben;ethylparaben; methylparaben; methylchloroisothiazoline;methylisothiazoline; a mixture of1,3-bis(hydroxymethyl)-5,5-dimethylhydantoin and 3-iodo-2-propynyl butylcarbamate; oxyquinoline; EDTA; tetrasodium EDTA; p-hydroxylbenzoic acidester; alkyl pyridinum compounds; coco phosphatidyl PG-dimoniumchloride; chlorhexidene digluconate; chlorhexidene acetate;chlorhexidene isethionate; chlorhexidene hydrochloride; benzalkoniumchloride; benzethonium chloride; polyhexamethylene biguanide, andmixtures thereof.
 5. The anti-microbial paper towel according to claim1, wherein the anti-microbial agent is2,4,4′-trichloro-2′-hydroxydiphenyl ether.
 6. The anti-microbial papertowel according to claim 1, wherein the anti-microbial agent comprises abenzalkonium chloride.
 7. The anti-microbial paper towel according toclaim 1, wherein the anti-microbial agent comprises a zinc salt.
 8. Theanti-microbial paper towel according to claim 1, wherein the pHbalancing agent comprises an organic acid.
 9. The anti-microbial papertowel according to claim 1, wherein the pH balancing agent comprises anorganic acid and a buffer combination.
 10. The anti-microbial papertowel according to claim 9, wherein the buffer combination comprisescitric acid and disodium phosphate.
 11. The anti-microbial paper towelaccording to claim 9, wherein the buffer combination comprises disodiumcitrate and sodium hydroxide.
 12. The anti-microbial paper towelaccording to claim 1, wherein the pH balancing agent is applied to theweb in an amount of from about 0.5% to about 3% by weight of the lotioncomposition.
 13. The anti-microbial paper towel according to claim 1,wherein the pH balancing agent is applied to the web in an amount offrom about 1% to about 2% by weight of the lotion composition.
 14. Theanti-microbial paper towel according to claim 1, wherein the pHbalancing agent comprises an alpha hydroxy acid, an alpha di-hydroxyacid, a beta hydroxy acid or combinations thereof.
 15. Theanti-microbial paper towel according to claim 14, wherein the pHbalancing agent is selected from glycolic acid, alpha-acetyl glycolicacid, lactic acid, tartaric acid, alpha-acetyl lactic acid,alpha-hydroxy isobutyric acid, salicylic acid, mandelic acid,ortho-acetyl mandelic acid, benzilic acid, ortho-acetyl benzilic acid,malic acid, citric acid, gluconic acid, pyruvic acid, sorbic acid andcombinations thereof.
 16. The anti-microbial paper towel according toclaim 14, wherein the pH balancing agent is citric acid.
 17. Theanti-microbial paper towel according to claim 14, wherein the pHbalancing agent is lactic acid.
 18. The anti-microbial paper towelaccording to claim 14, wherein the pH balancing agent is glycolic acid.19. The anti-microbial paper towel according to claim 1, wherein thepH-sensitive transfer indicator comprises thymol blue, bromo cresolpurple, methyl red, cresol red, phenolphthalein, thymolphthalein, orAlizarin yellow R.
 20. The anti-microbial paper towel according to claim1, wherein the pH-sensitive transfer indicator is thymol blue.
 21. Theanti-microbial paper towel according to claim 1, wherein the cellulosicweb is predominantly softwood fiber.
 22. The anti-microbial paper towelaccording to claim 1, wherein the web comprises a wet strength agent.23. The anti-microbial paper towel according to claim 22, wherein thewet strength agent is selected from aldehyde-containing polyols,aldehyde-containing cationic starch, glyoxal, glutaraldehyde,dialdehydes, boric acid carbonate, zirconium ammonium carbonate,glyoxalated polyacrylamide, polyamide-epichlorohydrin,polyamine-epichlorohydrin, urea-formaldehyde, melamine-formaldehyde,polyethyleneimine, and latex emulsions.
 24. The anti-microbial papertowel according to claim 1, wherein the transferable lotion compositiondisposed on the web is selected and applied in amounts such that itimparts a water absorption rate delay to the cellulosic web of at leastabout 50%.
 25. The anti-microbial paper towel according to claim 1,wherein the transferable lotion composition disposed on the web isselected and applied in amounts such that it imparts a water absorptiondelay to the cellulosic web of at least about 75%.
 26. Theanti-microbial paper towel according to claim 1, wherein thetransferable lotion composition disposed on the web is selected andapplied in amounts such that it imparts a water absorption delay to thecellulosic web of at least about 100%.
 27. The anti-microbial papertowel according to claim 1, wherein the unlotioned cellulosic web hassubstantially the same SAT value as the lotioned paper towel.
 28. Theanti-microbial paper towel according to claim 1, wherein the paper towelhas a SAT value of at least about 2 g/g.
 29. The anti-microbial papertowel according to claim 1, wherein the paper towel has a SAT value ofat least about 3 g/g.
 30. The anti-microbial paper towel according toclaim 1, wherein the paper towel has a SAT value of at least about 4g/g.
 31. The anti-microbial paper towel according to claim 1, whereinthe paper towel has a SAT value of at least about 4.5 g/g.
 32. Theanti-microbial paper towel according to claim 1, wherein the paper towelhas a SAT value of from about 2 g/g to about 5 g/g.
 33. Theanti-microbial paper towel according to claim 1, wherein the paper towelhas a WAR value of at least about 40 seconds.
 34. The anti-microbialpaper towel according to claim 1, wherein the paper towel has a WARvalue of at least about 50 seconds.
 35. The anti-microbial paper towelaccording to claim 1, wherein the paper towel has a WAR value of fromabout 55 seconds to about 75 seconds.
 36. The anti-microbial paper towelaccording to claim 1, wherein the paper towel has a WAR value of atleast about 100 seconds.
 37. The anti-microbial paper towel according toclaim 1, wherein the paper towel has a WAR value of at least about 120seconds.
 38. The anti-microbial paper towel according to claim 1,wherein the paper towel has a WAR value between bout 75 seconds and 200seconds.
 39. The anti-microbial paper towel according to claim 1,wherein the transferable lotion is applied to the cellulosic web in anamount of from about 3 weight percent to about 20 weight percent. 40.The anti-microbial paper towel according to claim 1, wherein thetransferable lotion is applied to the cellulosic web in an amount offrom about 5 percent by weight to about 15 percent by weight.
 41. Theanti-microbial paper towel according to claim 1, wherein thetransferable lotion is applied to the cellulosic web in an amount offrom about 8 percent by weight to about 10 percent by weight.
 42. Theanti-microbial paper towel according to claim 1, wherein the unlotionedcellulosic web has a basis weight of from about 15 g/m² to about 65g/m².
 43. The anti-microbial paper towel according to claim 1, whereinthe unlotioned cellulosic web has a basis weight of from about 25 g/m²to about 50 g/m².
 44. The anti-microbial paper towel according to claim1, wherein the unlotioned cellulosic web has a basis weight of fromabout 30 g/m² to about 40 g/m².
 45. The anti-microbial paper towelaccording to claim 1, wherein the cellulosic web comprises at leastabout 65 percent by weight softwood fiber.
 46. The anti-microbial papertowel according to claim 1, wherein the cellulosic web comprises atleast about 70 percent by weight softwood fiber.
 47. The anti-microbialpaper towel according to claim 1, wherein the cellulosic web comprisesfrom about 70 percent by weight softwood fiber to about 90 percent byweight softwood fiber.
 48. The anti-microbial paper towel according toclaim 1, wherein the cellulosic web is predominantly comprised of fiberselected form softwood fiber, recycle fiber and mixtures thereof. 49.The anti-microbial paper towel according to claim 1, wherein thecellulosic web comprises at least 50 percent by weight recycle fiber.50. The anti-microbial paper towel according to claim 1, wherein thecellulosic web comprises at least 60 percent by weight recycle fiber.51. The anti-microbial paper towel according to claim 1, wherein thecellulosic web comprises at least 70 percent by weight recycle fiber.52. The anti-microbial paper towel according to claim 1, wherein thecellulosic web comprises at least 80 percent by weight recycle fiber.53. The anti-microbial paper towel according to claim 1, wherein thecellulosic web comprises at least 90 percent by weight recycle fiber.54. The anti-microbial paper towel according to claim 1, wherein thefiber in the cellulosic web is 100% recycle fiber.
 55. Theanti-microbial paper towel according to claim 1, wherein the cellulosicweb consists predominantly of Douglas fir fiber.
 56. The anti-microbialpaper towel according to claim 1, wherein the towel has an eight sheetcaliper of from about 35 to about 90 mils, consists predominantly ofsoftwood fiber and is in the form of a single ply towel.
 57. Theabsorbent cellulosic sheet according to claim 1, wherein the cellulosicweb comprises at least about 70 percent by weight Douglas fir fiber. 58.An anti-microbial paper towel comprising: a) a cellulosic web; b) awaterless micro-emulsion which is substantially liquid at roomtemperature immobilized on the web in a semi-solid or solid state andselected and applied in amounts such that it imparts a water absorptionrate delay of at least about 75% to the cellulosic web; c) wherein, thewaterless mien-emulsion comprises an anti-microbial agent, a polaremollient, a non-polar emollient and a surfactant composition includinga nonionic surfactant; and wherein further the waterless micro-emulsionis capable of forming an aqueous micro-emulsion upon contact with water;d) a water soluble balancing agent disposed on the web at a plurality ofdiscrete pH balancing agent locations; and e) a pH-sensitive transferindicator disposed on the web at a plurality of discrete indicatorlocations which are apart from the pH balancing agent locations, whereinthe pH-sensitive transfer indicator is chromatically responsive to thebalancing agent in aqueous form; and wherein further the pH balancingagent and the pH-sensitive transfer indicator are selected and appliedto the web such that the pH-sensitive transfer indicator undergoes agradual color change upon contact with water to indicate effectivetransfer of the lotion, wherein the initiation of said color change isdetermined by the wicking time of the pH balancing agent.
 59. A papertowel with a chromatic transfer indicator comprising: a) a cellulosicweb; b) a water soluble pH balancing agent disposed on the web at aplurality of discrete pH balancing agent locations; c) a pH-sensitivetransfer indicator disposed on the web at a plurality of discreteindicator locations which are apart from the pH balancing agentlocations, wherein the pH-sensitive transfer indicator is chromaticallyresponsive to the pH balancing agent in aqueous form; and d) atransferable lotion composition immobilized on the cellulosic web in asemi-solid or solid form and imparting a water absorption rate delay tothe cellulosic web; wherein the pH balancing agent and the pH-sensitivetransfer indicator are selected and applied to the web such that thepH-sensitive transfer indicator undergoes a gradual color change uponcontact of the paper towel with water, wherein the initiation of saidcolor change is determined by the wicking time of the pH balancingagent.
 60. The paper towel according to claim 59, wherein the pHbalancing agent is selected from glycolic acid, alpha-acetyl glycolicacid, lactic acid, tartaric acid, alpha-acetyl lactic acid,alpha-hydroxy isobutyric acid, salicylic acid, mandelic acid,ortho-acetyl mandelic acid, benzilic acid, ortho-acetyl benzilic acid,malic acid, citric acid, gluconic acid, pyruvic acid, sorbic acid andcombinations thereof.
 61. The paper towel according to claim 59, whereinthe pH balancing agent is citric acid.
 62. The paper towel according toclaim 59, wherein the pH balancing agent is lactic acid.
 63. The papertowel according to claim 59, wherein the pH balancing agent is glycolicacid.
 64. The paper towel according to claim 59, wherein thepH-sensitive transfer indicator comprises thymol blue, bromo cresolpurple, methyl red, cresol red, phenolphthalein, thymolphthalein, orAlizarin yellow R.
 65. The paper towel according to claim 59, whereinthe pH-sensitive transfer indicator is thymol blue.